XANA, the primary adversary of Team Lyoko, is a highly sophisticated multi-agent artificial intelligence, whose goal is to destroy/conquer humanity. It serves as the main antagonist of the show.

XANA, as well as Lyoko, was originally created by Franz Hopper to destroy Project Carthage, a computer program designed to monitor enemy of the state communications for the French government. However, over time XANA developed independence, and when Franz Hopper and his daughter Aelita came to Lyoko to hide from the French Secret Service, XANA took the chance to imprison Hopper and steal Aelita's memories. It is believed Franz Hopper managed to shut down the supercomputer before XANA could acquire any more power.

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